@article{Venkaiah_Thathapudi_Sainath_2019, title={Detection and mode of action of retinoids on ovarian development in the mud crab, Scylla serrata}, volume={7}, url={http://ij-aquaticbiology.com/index.php/ijab/article/view/687}, DOI={10.22034/ijab.v7i5.687}, abstractNote={<p>In the current study, the retinoic acid isomers such as 9-<em>cis </em>retinoic acid and all-<em>trans </em>retinoic acid were detected in the mature ovaries of mud crabs, <em>Scylla serrata </em>using HPLC<em> </em>analysis. Given the detection of retinoids in the ovaries, an attempt has been made to<em> </em>elucidate the possible role of retinoic acid in the regulation of reproduction in mud crabs.<em> </em>Injection of 9-<em>cis </em>retinoic acid induced ovarian maturation in intact mud crabs as evidenced<em> </em>by a significance elevation in the ovarian index (226.76%; <em>P</em><0.001), and oocyte diameter<em> </em>(150.61%; <em>P</em><0.001) accompanied by accumulation of yolk globules in the oocytes as<em> </em>compared to the untreated crabs. Further, a significant increase (258.63%; <em>P</em><0.0001) in the<em> </em>circulatory ecdysteroid levels were also observed in 9-<em>cis </em>retinoic acid injected mud crabs<em> </em>over vehicle injected crabs. From the results, it can be postulated that retinoic acid-induced<em> </em>stimulation of ovarian maturation at least in part mediates ecdysteroids in the mud crabs., 0.371 and 0.217 year<sup>-1</sup>, respectively and the exploitation rate was calculated as 0.369. <br /><em></em></p>}, number={5}, journal={International Journal of Aquatic Biology}, author={Venkaiah, Kaduru and Thathapudi, Daveedu and Sainath, Sri Bhashyam}, year={2019}, month={Nov.}, pages={245–253} }