Evaluation of toxicity and biochemical effects of the Oxadiargyl in Common carp (Cyprinus carpio L.)

Hossein Emadi; Somayeh Shariatzadeh; Shahla Jamili; Ali Mashinchian

doi:10.22034/ijab.v6i2.466

Authors

Hossein Emadi
[email protected]
Department of Marine Biology, Faculty of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Somayeh Shariatzadeh Department of Marine Biology, Faculty of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Shahla Jamili Iranian Fisheries Research Organization, Agriculture Research Education and Extension Organization (AREEO), Tehran, Iran.
Ali Mashinchian Department of Marine Biology, Faculty of Marine Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Vol. 6 No. 2 (2018): April

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April 25, 2018

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This study aimed to investigate the effects of sublethal concentrations of oxadiargyl herbicide on growth performance, serum biochemical parameters and liver histology of the common carp, Cyprinus carpio, during 30 days exposure period. Carp fingerlings were randomly divided into four duplicate groups. Experimental groups were exposed to the concentration of 0.1, 0.3 and 0.5 ppm of oxadiargyl, while the control group was kept in toxicant free. During the experiment, none of the control fish died. Weight gain and condition factor decreased, while food conversion ratio increased in fish exposed to 0.5 ppm of oxadiargyl. Exposure to oxadiargyl significantly increased serum ALT, AST and ALP, as well as glucose levels, while cholesterol, total protein and albumin were significantly decreased in the exposed fish groups depend on oxadiargyl concentrations and exposure time. Diffuse and focal necrosis mainly as perivascular necrosis fibrosis, increase in size and number of melanomacrophage centers, bile duct hyperplasia, hyperemia and hemorrhage, fatty changes in the hepatocytes, fibrocyte aggregation and focal inflammatory cells were also the histological lesions observed in the liver of exposed fish. These results showed that oxadiargyl is highly toxic to common carp and had negative effects on the growth performance, serum biochemical parameters and the liver tissue of common carp.

Emadi, H., Shariatzadeh, S., Jamili, S., & Mashinchian, A. (2018). Evaluation of toxicity and biochemical effects of the Oxadiargyl in Common carp (Cyprinus carpio L.). International Journal of Aquatic Biology, 6(2), 55–60. https://doi.org/10.22034/ijab.v6i2.466

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